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O2genes

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The Ritual of Hyperbaric Oxygen and Lessons for the Treatment of Persistent Post-concussion Symptoms in Military Personnel

Read white paper here. Authors: Charles W Hoge, Wayne B Jonas This paper reflects significant improvements in post-concussion symptoms and also secondary outcomes including post-traumatic stress disorder, depression, improved sleep quality, satisfaction with life, physical, cognitive and emotional health function

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Hyperbaric Oxygen Therapy: A Treatment for Radiation Induced Plexopathy (P3.4-027)

Read white paper here. Authors: Geeta Verma, Carolyn Goldschmidt, Susan Vaughan Objective: To present a case report of hyperbaric oxygen as potential therapy for radiation induced plexopathy. Background: Radiation induced plexopathy results after radiation treatment is targeted at pelvic malignancies. It typically presents with motor and sensory changes in lower extremities (LEs), although, due to the various anatomic sites …

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Hyperbaric oxygen therapy for the treatment of long COVID: early evaluation of a highly promising intervention

Read white paper here. Authors: Tim Robbins, Michael Gonevski, Cain Clark, Sudhanshu Baitule, Kavi Sharma, Angel Magar, Kiran Patel, Sailesh Sankar, Ioannis Kyrou, Asad Ali, Harpal S Randeva Background: Long COVID is a common occurrence following COVID-19 infection. The most common symptom reported is fatigue. Limited interventional treatment options exist. We report the first evaluation of hyperbaric oxygen therapy (HBOT) for long COVID treatment. Methods: A total …

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Hyperbaric oxygen: B-level evidence in mild traumatic brain injury clinical trials

Read white paper here. Authors: Xavier A Figueroa, James K Wright  Objective: First, to demonstrate that B-level evidence exists for the use of hyperbaric oxygen therapy (HBOT) as an effective treatment in mild to moderate traumatic brain injury/persistent postconcussion syndrome (mTBI/PPCS). Second, to alert readers and researchers that currently used pressurized air controls (≥21% O2, >1.0 ATA) …

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Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury – randomized prospective trial

Read white paper here. Background: Traumatic brain injury (TBI) is the leading cause of death and disability in the US. Approximately 70-90% of the TBI cases are classified as mild, and up to 25% of them will not recover and suffer chronic neurocognitive impairments. The main pathology in these cases involves diffuse brain injuries, which are …

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HIV: reactive oxygen species, enveloped viruses and hyperbaric oxygen

Read white paper here. This paper demonstrates that there are many examples in the literature of contradictory data concerning reactive oxygen intermediates (ROIs), responsible for producing cellular oxidative stress (OS), and their enhancement or diminution of viral replication. Nevertheless, ROIs repeatedly have been shown to be virucidal against enveloped-viruses, like the human immunodeficiency virus (HIV). …

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Hyperbaric oxygen therapy may improve symptoms in autistic children

Read white paper here. Abstract Autism is a neurodevelopmental disorder that currently affects as many as 1 out of 166 children in the United States. Recent research has discovered that some autistic individuals have decreased cerebral perfusion, evidence of neuroinflammation, and increased markers of oxidative stress. Multiple independent single photon emission computed tomography (SPECT) and …

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Effects of hyperbaric oxygen at 1.25 atmospheres absolute with normal air on macrophage number and infiltration during rat skeletal muscle regeneration

Read white paper here. Abstract Use of mild hyperbaric oxygen less than 2 atmospheres absolute (2026.54 hPa) with normal air is emerging as a common complementary treatment for severe muscle injury. Although hyperbaric oxygen at over 2 atmospheres absolute with 100% O2 promotes healing of skeletal muscle injury, it is not clear whether mild hyperbaric …

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An Update on the Appropriate Role for Hyperbaric Oxygen: Indications and Evidence

Read white paper here. Abstract Background: Among advanced therapeutic interventions for wounds, hyperbaric oxygen therapy (HBOT) has the unique ability to ameliorate tissue hypoxia, reduce pathologic inflammation, and mitigate ischemia reperfusion injury. Most of the conditions for which it is utilized have few successful alternative treatments, and the morbidity and mortality associated with treatment failure are …

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