{"id":2926,"date":"2022-01-21T16:10:00","date_gmt":"2022-01-21T08:10:00","guid":{"rendered":"https:\/\/o2genes.com\/?p=2926"},"modified":"2025-05-28T17:11:09","modified_gmt":"2025-05-28T09:11:09","slug":"meta-analysis-on-the-efficacy-and-safety-of-hyperbaric-oxygen-as-adjunctive-therapy-for-vascular-dementia","status":"publish","type":"post","link":"https:\/\/o2genes.com\/ch\/\u9ad8\u538b\u6c27\u4f5c\u4e3a\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u8f85\u52a9\u7597\u6cd5\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\/","title":{"rendered":"\u9ad8\u538b\u6c27\u8f85\u52a9\u6cbb\u7597\u8840\u7ba1\u6027\u75f4\u5446\u7597\u6548\u548c\u5b89\u5168\u6027\u7684\u835f\u8403\u5206\u6790"},"content":{"rendered":"<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">\u672c\u6307\u5357\u4ecb\u7ecd\u9ad8\u538b\u6c27\u4f5c\u4e3a\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u8f85\u52a9\u7597\u6cd5\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684 Meta \u5206\u6790\u3002\u8840\u7ba1\u6027\u75f4\u5446\u662f\u4e00\u79cd\u56e0\u8111\u90e8\u8840\u6d41\u91cf\u51cf\u5c11\u800c\u5bfc\u81f4\u7684\u75be\u75c5\uff0c\u901a\u5e38\u662f\u7531\u4e8e\u4e2d\u98ce\u6216\u5176\u4ed6\u8840\u7ba1\u95ee\u9898\u5f15\u8d77\u7684\u3002\u5b83\u4f1a\u5bfc\u81f4\u8ba4\u77e5\u80fd\u529b\u4e0b\u964d\u548c\u8bb0\u5fc6\u95ee\u9898\uff0c\u4e25\u91cd\u5f71\u54cd\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u3002\u9ad8\u538b\u6c27\u7597\u6cd5\uff08HBOT\uff09\u4f5c\u4e3a\u4e00\u79cd\u6cbb\u7597\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u7684\u8f85\u52a9\u7597\u6cd5\u53d7\u5230\u4e86\u5e7f\u6cdb\u5173\u6ce8\uff0c\u5b83\u5177\u6709\u6539\u5584\u8ba4\u77e5\u529f\u80fd\u7684\u6f5c\u529b\u3002\u672c\u6587\u63a2\u8ba8\u4e86\u9ad8\u538b\u6c27\u7597\u6cd5\u5728\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u4e2d\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u7684\u835f\u8403\u5206\u6790\uff0c\u4e3a\u9ad8\u538b\u6c27\u7597\u6cd5\u4f5c\u4e3a\u4e00\u79cd\u8f85\u52a9\u6cbb\u7597\u65b9\u6cd5\u63d0\u4f9b\u4e86\u89c1\u89e3\u3002<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u80cc\u666f\u4ecb\u7ecd<\/strong>&nbsp;\u8840\u7ba1\u6027\u75f4\u5446\uff08VD\uff09\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u8001\u5e74\u75be\u75c5\u3002\u5927\u91cf\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\uff0c\u9ad8\u538b\u6c27\u662f\u6cbb\u7597\u8870\u8001\u76f8\u5173\u75be\u75c5\u7684\u4e00\u79cd\u6709\u6548\u800c\u5b89\u5168\u7684\u8f85\u52a9\u7597\u6cd5\u3002\u7136\u800c\uff0c\u76ee\u524d\u8fd8\u6ca1\u6709\u53ef\u9760\u7684\u7cfb\u7edf\u6027\u8bc1\u636e\u8868\u660e <a href=\"https:\/\/o2genes.com\/ch\/\" title=\"\">\u9ad8\u538b\u6c27\u7597\u6cd5<\/a> (HBOT\uff09\u6cbb\u7597 VD\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u8fdb\u884c\u4e86\u4e00\u9879\u835f\u8403\u5206\u6790\uff0c\u4ee5\u8bc4\u4f30 HBOT \u6cbb\u7597 VD \u7684\u4e34\u5e8a\u7597\u6548\u548c\u5b89\u5168\u6027\u3002&nbsp;<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u65b9\u6cd5<\/strong>&nbsp;\u6211\u4eec\u6709\u6761\u4e0d\u7d0a\u5730\u4ece 8 \u4e2a\u6570\u636e\u5e93\uff08PubMed\u3001Cochrane Library\u3001Embase\u3001Web of Science\u3001Sino-Med\u3001\u4e2d\u56fd\u77e5\u7f51\uff08CNKI\uff09\u3001\u4e2d\u56fd\u79d1\u6280\u671f\u520a\u6570\u636e\u5e93\uff08VIP\uff09\u548c\u4e07\u65b9\uff09\u4e2d\u68c0\u7d22\u4e86\u4ece\u5f00\u59cb\u5230 2018 \u5e74 11 \u6708\u7684\u4e34\u5e8a\u7814\u7a76\u3002\u91c7\u7528RevMan 5.3.5\u8fdb\u884c\u8d28\u91cf\u8bc4\u4f30\u548c\u6570\u636e\u5206\u6790\u3002\u91c7\u7528Stata 15.1\u8fdb\u884c\u53d1\u8868\u504f\u501a\u68c0\u6d4b\u548c\u654f\u611f\u6027\u5206\u6790\u3002&nbsp;<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u7ed3\u679c<\/strong>&nbsp;\u670925\u9879\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\uff08RCT\uff09\u7b26\u5408\u6211\u4eec\u7684\u7eb3\u5165\u6807\u51c6\uff0c\u6d89\u53ca1954\u540d\u60a3\u8005\u3002\u8fd9\u4e9b\u6587\u7ae0\u7814\u7a76\u4e86 HBOT + \u5965\u62c9\u897f\u5766 + \u4f20\u7edf\u7597\u6cd5\uff08CT\uff09\u4e0e\u5965\u62c9\u897f\u5766 + CT (<em>n<\/em>&nbsp;= 13\uff09\u3001HBOT + \u4e01\u82ef\u915e + CT \u4e0e\u4e01\u82ef\u915e + CT (<em>n<\/em>&nbsp;= 5\uff09\u3001HBOT + \u591a\u5948\u54cc\u9f50 + CT \u4e0e\u591a\u5948\u54cc\u9f50 + CT (<em>n<\/em>&nbsp;= 4\uff09\uff0cHBOT + \u5c3c\u9ea6\u89d2\u6797 + CT \u4e0e\u5c3c\u9ea6\u89d2\u6797 + CT (<em>n<\/em>&nbsp;= 2\uff09\u548c HBOT + CT \u4e0e CT (<em>n<\/em>&nbsp;= 1).\u7ed3\u679c\u8868\u660e\uff0c\u989d\u5916\u7684 HBOT \u663e\u8457\u6539\u5584\u4e86\u60a3\u8005\u7684\u8ff7\u4f60\u7cbe\u795e\u72b6\u6001\u68c0\u67e5\uff08MMSE\uff09(<em>MD<\/em>&nbsp;= 4.00; 95%&nbsp;<em>CI<\/em>&nbsp;= 3.28-4.73;&nbsp;<em>P<\/em>&nbsp;&lt; 0.00001\uff09\u3001\u65e5\u5e38\u751f\u6d3b\u6d3b\u52a8\u80fd\u529b\uff08ADL\uff09 (<em>MD<\/em>&nbsp;= -5.91; 95%&nbsp;<em>CI<\/em>&nbsp;= -6.45, -5.36;&nbsp;<em>P<\/em>&nbsp;&lt; 0.00001\uff09\u548c\u6309\u5df4\u7279\u5c14\u6307\u6570\uff08BADL\uff09\u8ba1\u7b97\u7684 ADL (<em>MD<\/em>&nbsp;= 13.86; 95%&nbsp;<em>CI<\/em>&nbsp;= 5.63-22.10;&nbsp;<em>P<\/em>&nbsp;= 0.001\uff09\uff0c\u5e76\u63d0\u9ad8\u4e86\u603b\u6709\u6548\u7387\uff08TEF\uff09 (<em>\u6216<\/em>&nbsp;= 4.84, 95%&nbsp;<em>CI<\/em>&nbsp;= 3.19-7.33,&nbsp;<em>P<\/em>&nbsp;&lt; 0.00001).HBOT\u7ec4\u548cCT\u7ec4\u7684\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u5728\u7edf\u8ba1\u5b66\u4e0a\u65e0\u663e\u8457\u5dee\u5f02 (<em>\u6216<\/em>&nbsp;= 0.85, 95%&nbsp;<em>CI<\/em>&nbsp;= 0.26-2.78,&nbsp;<em>P<\/em>&nbsp;= 0.79).&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u9ad8\u538b\u6c27\u4f5c\u4e3a\u8f85\u52a9\u7597\u6cd5\u7684\u5e38\u89c1\u95ee\u9898<\/h2>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u95ee\u9898 1\uff1a \u4ec0\u4e48\u662f\u8840\u7ba1\u6027\u75f4\u5446\uff0c\u4e3a\u4ec0\u4e48\u5b83\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u533b\u5b66\u95ee\u9898\uff1f<\/strong> <\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">\u7b541: \u8840\u7ba1\u6027\u75f4\u5446\u662f\u4e00\u79cd\u8ba4\u77e5\u969c\u788d\uff0c\u901a\u5e38\u662f\u7531\u4e8e\u8840\u7ba1\u95ee\u9898\u6216\u4e2d\u98ce\u5bfc\u81f4\u8111\u90e8\u8840\u6d41\u53d7\u963b\u3002\u8840\u7ba1\u6027\u75f4\u5446\u4f1a\u5bfc\u81f4\u8bb0\u5fc6\u529b\u51cf\u9000\uff0c\u5e76\u4e14 <a href=\"https:\/\/www.cdc.gov\/aging\/data\/subjective-cognitive-decline-brief.html#:~:text=Cognitive%20decline%20can%20range%20from,to%20interfere%20with%20daily%20life.&amp;text=Alzheimer's%20disease%20is%20the%20most%20common%20form%20of%20dementia.\" title=\"\">\u8ba4\u77e5<\/a> \u8870\u9000\uff0c\u5f71\u54cd\u65e5\u5e38\u751f\u6d3b\u3002<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u95ee\u9898 2\uff1a \u4ec0\u4e48\u662f\u9ad8\u538b\u6c27\u7597\u6cd5\uff08HBOT\uff09\uff1f<\/strong> <\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">\u7b542\uff1a HBOT\u662f\u4e00\u79cd\u5728\u52a0\u538b\u8231\u4e2d\u547c\u5438\u7eaf\u6c27\u7684\u533b\u7597\u65b9\u6cd5\u3002\u5b83\u80fd\u63d0\u9ad8\u4f53\u5185\u7684\u542b\u6c27\u91cf\uff0c\u4fc3\u8fdb\u4f24\u53e3\u6108\u5408\uff0c\u5e76\u6709\u53ef\u80fd\u6539\u5584\u8ba4\u77e5\u529f\u80fd\u3002<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u95ee\u98983\uff1a HBOT\u5982\u4f55\u4f5c\u4e3a\u8840\u7ba1\u6027\u75f4\u5446\u7684\u8f85\u52a9\u7597\u6cd5\uff1f<\/strong> <\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">A3\uff1aHBOT\u4f5c\u4e3a\u4e00\u79cd\u8f85\u52a9\u7597\u6cd5\uff0c\u4e0e\u8840\u7ba1\u6027\u75f4\u5446\u7684\u6807\u51c6\u7597\u6cd5\u4e00\u8d77\u8fdb\u884c\u63a2\u8ba8\u3002\u835f\u8403\u5206\u6790\u662f\u4e00\u79cd\u7edf\u8ba1\u6280\u672f\uff0c\u5b83\u7efc\u5408\u5e76\u5206\u6790\u591a\u9879\u7814\u7a76\u7684\u7ed3\u679c\uff0c\u4ece\u800c\u5c31 HBOT \u6cbb\u7597\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u5f97\u51fa\u66f4\u53ef\u9760\u7684\u7ed3\u8bba\u3002<\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\"><strong>\u95ee\u9898 4\uff1a\u4f7f\u7528 HBOT \u6cbb\u7597\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u6709\u54ea\u4e9b\u6f5c\u5728\u76ca\u5904\u548c\u98ce\u9669\uff1f<\/strong> <\/p>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">\u7b54 4\uff1a\u6f5c\u5728\u7684\u76ca\u5904\u5305\u62ec\u6539\u5584\u8ba4\u77e5\u529f\u80fd\u548c\u63d0\u9ad8\u751f\u6d3b\u8d28\u91cf\u3002\u98ce\u9669\u53ef\u80fd\u5305\u62ec\u6c14\u538b\u521b\u4f24\u3001\u6c27\u4e2d\u6bd2\u548c\u9700\u8981\u4e13\u95e8\u8bbe\u65bd\u3002\u5982\u4f55\u5e73\u8861\u76ca\u5904\u4e0e\u98ce\u9669\u662f\u7814\u7a76\u7684\u91cd\u70b9\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u7ed3\u8bba<\/h2>\n\n\n\n<p class=\"has-ast-global-color-8-color has-text-color has-medium-font-size\">\u9274\u4e8e HBOT \u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u672c\u835f\u8403\u5206\u6790\u5efa\u8bae\u5c06 HBOT \u4f5c\u4e3a\u6cbb\u7597\u8840\u7ba1\u6027\u75f4\u5446\u75c7\u7684\u4e00\u79cd\u6709\u6548\u800c\u5b89\u5168\u7684\u8f85\u52a9\u7597\u6cd5\u3002\u00a0<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/wa.link\/iwnw8n\" style=\"background-color:#38a533\">\u8054\u7cfb\u6211\u4eec<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>This guide is about Meta-Analysis on the Efficacy and Safety of Hyperbaric Oxygen as Adjunctive Therapy for Vascular Dementia. Vascular dementia is a condition caused by reduced blood flow to the brain, often due to strokes or other vascular issues. It can lead to cognitive decline and memory problems, significantly impacting the quality of life [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[124,122],"tags":[78,77,89,123],"class_list":["post-2926","post","type-post","status-publish","format-standard","hentry","category-hbot-for-alzheimer-and-dementia","category-oxygen-research","tag-hbot","tag-hyperbaric-oxygen","tag-hyperbaric-oxygen-therapy","tag-research"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/posts\/2926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/comments?post=2926"}],"version-history":[{"count":0,"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/posts\/2926\/revisions"}],"wp:attachment":[{"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/media?parent=2926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/categories?post=2926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/o2genes.com\/ch\/wp-json\/wp\/v2\/tags?post=2926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}